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These researchers sequenced the coding region of the NOD2 gene and genotyped an insertion polymorphism affecting the leucine-rich region of the protein product in 512 individuals with IBD from 309 German or British families, 369 German trios (namely, German patients with sporadic IBD and their unaffected parents), and 272 normal controls.

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The safety and efficacy of IMURAN for the treatment of Crohn's disease and ulcerative colitis have not been established.

Vikram Deshpande; Yoh Zen; John KC Chan; Eunhee E Yi; Yasuharu Sato; Tadashi Yoshino; Günter Klöppe; J Godfrey Heathcote; Arezou Khosroshahi; Judith A Ferry; Rob C Aalberse; Donald B Bloch; William R Brugge; Adrian C Bateman; Mollie N Carruthers; Suresh T Chari; Wah Cheuk; Lynn D Cornell; Carlos Fernandez-Del Castillo; David G Forcione; Daniel L Hamilos; Terumi Kamisawa; Satomi Kasashima; Shigeyuki Kawa; Mitsuhiro Kawano; Gregory Y Lauwers; Yasufumi Masaki; Yasuni Nakanuma; Kenji Notohara; Kazuichi Okazaki; Ji Kon Ryu; Takako Saeki; Dushyant V Sahani; Thomas C Smyrk; James R Stone; Masayuki Takahira; George J Webster; Motohisa Yamamoto; Giuseppe Zamboni; Hisanori Umehara; John H Stone (18 May 2012).

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My next media encounter with this issue occurred on November 12, 2000. This time it was 60 Minutes.

Some of the major issues with long-term use of infliximab include the risk of infection and rare cases of lymphoma.

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The structural similarities found between the epitopes of CYP2D6 and herpes simplex virus as well as between FTCD and herpes virus type 6 indicate that antigen cross-reactions may have a significant role in AIH pathogenesis.

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Most of the data regarding pregnancy and disease activity has relied on clinical remission.

Ciprofloxacin (Cipro) is also effective in patients with Crohn's disease, and it can be combined with metronidazole.

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We have now followed these 25 patients for 10 years and have treated an additional 47 patients in a similar manner.

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Later, it can cause fatigue, a general feeling of illness (malaise), and depression.

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The authors wish to thank Mrs M Shields for help in English revision.

Alfred I. Neugut, MD, PhD, of Columbia University, New York, suggests the study gives physicians another weapon in their arsenal against colon cancer.

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