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The safety and efficacy of IMURAN for the treatment of Crohn's disease and ulcerative colitis have not been established.
Vikram Deshpande; Yoh Zen; John KC Chan; Eunhee E Yi; Yasuharu Sato; Tadashi Yoshino; Günter Klöppe; J Godfrey Heathcote; Arezou Khosroshahi; Judith A Ferry; Rob C Aalberse; Donald B Bloch; William R Brugge; Adrian C Bateman; Mollie N Carruthers; Suresh T Chari; Wah Cheuk; Lynn D Cornell; Carlos Fernandez-Del Castillo; David G Forcione; Daniel L Hamilos; Terumi Kamisawa; Satomi Kasashima; Shigeyuki Kawa; Mitsuhiro Kawano; Gregory Y Lauwers; Yasufumi Masaki; Yasuni Nakanuma; Kenji Notohara; Kazuichi Okazaki; Ji Kon Ryu; Takako Saeki; Dushyant V Sahani; Thomas C Smyrk; James R Stone; Masayuki Takahira; George J Webster; Motohisa Yamamoto; Giuseppe Zamboni; Hisanori Umehara; John H Stone (18 May 2012).
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My next media encounter with this issue occurred on November 12, 2000. This time it was 60 Minutes.
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Response criteria were the number of patients in remission after 16 weeks without steroids (primary) and remission after 24 weeks, frequency of side effects, and quality of life (secondary).
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Most of the data regarding pregnancy and disease activity has relied on clinical remission.
Ciprofloxacin (Cipro) is also effective in patients with Crohn's disease, and it can be combined with metronidazole.
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The other 23 patients remained in remission with the higher dose of azathioprine alone for a median of 109 months (range, 39 to 128).
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We have now followed these 25 patients for 10 years and have treated an additional 47 patients in a similar manner.
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The authors wish to thank Mrs M Shields for help in English revision.
Alfred I. Neugut, MD, PhD, of Columbia University, New York, suggests the study gives physicians another weapon in their arsenal against colon cancer.
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What is the likely hood that the disease will return?
One of the reasons that former paramedics make good CCT nurses is because they have the right responses to critical changes in patient condition.
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